How this index is made

humanpeptides.fyi is an index of what has been studied, published, said and reported about peptides and related compounds used or studied in humans. This page explains where the content comes from, how it is checked, and what the labels on each entry mean.

Index last reviewed: [INDEX REVIEW DATE]

Who compiles it

[CONFIRM before publishing: who compiles the index; whether AI research tools were used to find, read and summarize sources; and whether any physician or pharmacist reviewed the content. State each plainly here. Do not imply clinical review that did not happen.]

The Site makes no claims of its own

humanpeptides.fyi does not claim that any compound does anything. Every benefit, effect, side effect, nickname and quote on the Site is a report of what someone else has published, stated or posted: a regulator, a trial, a journal article, a product label, a reference work, a news story, an explainer site, a clinic, a seller or a member of an online community. The Site organizes those reports and links to each one so you can read it yourself.

When an entry says a compound “improved” something or is “used for” something, read it as “the cited source reports that”. The only things the Site adds are organization: plain-language titles, the evidence label on each entry, groupings by family and goal, and labels describing each type of source.

Where the content comes from

Each entry is compiled from the sources linked on that entry. They include regulators and official labels, clinical trial registries, peer-reviewed research, reference works, news reports, explainer and guide sites, clinic and seller pages, and community forums.

For each compound the index records what it is, the three outcomes most discussed for it in those sources, notes on six body systems (tissues, hormones, cells and mitochondria, brain and sleep, weight and metabolism, muscle), other notable points, reported side effects and risks, and a summary of the evidence. Each statement links to the sources it was drawn from. Where several statements sit under one benefit and the sources cannot be pinned to a single statement, the links are shown once for the whole benefit, so a given link may support only part of what is listed.

The Sources page also publishes a ranked list of 50 sources on peptide research in humans, with notes on what each is known for and why it ranks where it does. The ranking reflects the compiler’s judgment of how authoritative each source is.

Every source that informed the index is linked on the Site, including weak ones such as seller pages and forum posts. This is deliberate: you can always see what a statement rests on. The source-type label tells you how much weight it can bear.

Publications consulted

Four publications were consulted to check names and aliases, add context, and find further sources:

Dr. Axe, Peptides A-Z guide (draxe.com)
PepEdHub, peptide index (pepedhub.com)
Seek Peptides, complete peptide list (seekpeptides.com)
NCBI PMC (pmc.ncbi.nlm.nih.gov), the free full-text archive of biomedical and life-science journal literature at the US National Library of Medicine

The first three are consumer-facing publications and are labelled “explainer” when cited. An article’s presence in PMC is not a judgment of its quality by the National Library of Medicine; we label PMC articles “research” and you should still read the study itself.

When we restate a point from one of these publications, we write it in our own words, keep it to 35 words or fewer, name the publication, and link to the page. Consulting a publication is not an endorsement of it, and none of them has reviewed or endorsed this Site.

How quotes are selected and verified

A quote appears only if all of the following are true:

It is copied word for word from a page that was actually fetched, with no words added or changed and no ellipses unless the source has them.
It is 40 words or fewer.
It is attributed to the speaker or publication and links to the page it came from.
It carries one plain line of context, such as the study design and who was studied.
Its exact text and link are recorded as verified. The build is configured to publish only quotes recorded as verified. [CONFIRM: describe how a quote is verified, for example an automated match against a fresh copy of the page, a human check, or both; and confirm the build blocks quotes when no verification record exists.]

We prefer quotes that state a finding or a position directly: the conclusion of a study, a regulator’s statement, the wording of an official label. Each quote is tagged by who is speaking: researcher, clinician, regulator, journalist, manufacturer, or testimonial.

Testimonials from forums and social media are attributed only as “Anonymous user, r/[community]” or “Anonymous forum user, [site]”. They are written to exclude usernames. If you wrote a post that is quoted here and want the quote removed, email us and we will remove it.

Quotes and paraphrased points are written to exclude doses, dose schedules, mixing or injection instructions, sellers and prices.

Evidence tiers

Each entry gets one of five tiers. The tier describes the strongest human or regulatory evidence we found for the compound, product or blend as a whole. It does not rate any single benefit listed on the entry. It is not a rating of safety, and it is not a rating of how well something works. A higher tier does not mean a compound is safer or better for you.

Tiers are editorial judgments, assigned in one central file, and are not regulatory determinations.

Approved (specific use). At least one product containing the compound is approved by the FDA or another major regulator for a specific use. The approval covers that product, use, patient group and dose only. Benefits shown on the entry may fall outside it. For example, an approval to treat a nutrient deficiency does not cover fat loss or energy in people who are not deficient.
Trial-backed. Larger randomized human trials have been published, whether the results were positive or negative, but there is no US approval for the uses discussed. A compound can be Trial-backed because its trials failed.
Early human. Some human data exist, but only from small, short, old, unblinded, uncontrolled or single-group studies. Results are preliminary.
Preclinical. The evidence is mostly from cell and animal studies. Effects, doses and safety in humans are unknown.
Unstudied. We found no direct published studies of this product or blend. What is said about it rests on anecdotes, marketing claims, or studies of its separate ingredients, which may not apply to the combination.

What kind of compound it is

Each entry is labelled as one of three kinds:

Peptide. A short chain of amino acids.
Non-peptide. A nutrient, small molecule or other substance that is not a peptide, such as L-carnitine, NAD+ or vitamin B12. These are included because they are commonly sold, combined or discussed alongside peptides, and people look for them in the same place.
Blend. A combination of compounds sold or discussed under one name. Many blend names were coined by sellers or online communities. Their contents are not standardized and can differ from seller to seller.

Source-type labels

Every cited link carries one of ten labels:

Regulator. Government health agencies, drug regulators and official government publications.
Registry. Clinical trial registries. A registry entry shows that a trial was planned or run; it may not include results.
Research. Journal articles, conference abstracts, preprints, literature databases and research-summary services. Not all of these are peer-reviewed. Preprints and abstracts usually are not.
Label. Prescribing information, product labels and official announcements from the company that makes the product, including press releases.
Reference. Drug references, encyclopedias and professional education websites.
News. News and magazine outlets.
Explainer. Consumer-facing websites, guides, wikis, blogs and apps that explain peptides in general terms. Quality varies widely. Many are not written by clinicians, and some may have commercial ties.
Clinic. Telehealth services, clinics and compounding pharmacies. These are businesses that may prescribe or sell the compounds discussed.
Vendor. Businesses that sell the compound or a product containing it, including sellers of products labelled “research use only.”
Community. Reddit, forums and other online communities. These are unverified personal reports.

Labels describe the website, not the individual page. They are assigned from a list of known websites we maintain. A website not on that list is labelled by an automatic rule that treats unrecognized websites as vendors, so a label can be wrong. Tell us if you find one that is.

Why vendor, clinic and community pages appear at all

Vendor, clinic and community pages are cited because, for some compounds and blends, they are where a claim, an ingredient list or a user experience was actually published. Removing those links would make weak claims look better supported than they are. Labelling them lets you see exactly what a statement rests on.

A citation is not an endorsement. Some of these links go to product pages, because that is where the claim appeared. Do not treat them as places to buy. We receive nothing of value from any seller, clinic or manufacturer, and the Site has no advertising or affiliate links. [CONFIRM with operator.]

How the three benefits are chosen

Each entry shows up to three benefits. They are the three outcomes the compiler identified as most discussed for that compound in the sources reviewed, in order of how prominently they are discussed. [CONFIRM: the basis for choosing and ranking them.]

Here, “benefit” means an outcome people discuss, not an effect that has been shown. The title of each benefit is written to say plainly how well it is supported. A listed benefit can be unproven, extrapolated from a related compound, seen only in animals, or a negative result. Examples from the index include “Fat loss, failed in trials”, “Skin support, extrapolated”, “Cardiac repair, preclinical” and “Injury recovery, anecdotal”.

Every benefit shows the statements behind it, with a note on the type of evidence where one was recorded (for example “human RCT”, “animal” or “anecdotal”), and the source links for that benefit. Links are recorded per benefit, so a link may support only some of the statements listed under it. Open the source to see exactly what it says.

Goals such as Fat Loss & Metabolism or Sleep group entries by the benefits discussed for them. An entry appearing under a goal means it has been discussed for that goal, not that it achieves it.

Doses and amounts

We do not give dosing guidance. Some study summaries state the amount used in a trial, because the result cannot be described accurately without it. Amounts, schedules, timing tips and product compositions reported by sellers or online communities are removed from our summaries.

Side effects and risks

Side effects and risks are listed as reported in the cited sources. The list is not complete. An entry with few listed risks has not been shown to be safe.

Images

Photographs of people and of the body on the Site are AI-generated illustrations. They do not show real people or the results of using any compound.

Updates

Research and regulatory status change. The index was last reviewed on the date shown at the top of this page. Check the original source, and a regulator or licensed professional, for current information.

How to report an error

Email [CONTACT EMAIL] with:

the address of the page;
the statement you think is wrong, outdated or mislabelled; and
if you can, a source that supports the correction.

We check reports against the cited sources and correct, relabel or remove content when warranted. [CONFIRM: target response time.] We cannot answer personal medical questions.