Evidence labels, explained.
Every one of the 48 entries carries one of 5 evidence labels, so a promising animal study never reads like an approved drug. Below, each label with its definition and the compounds that carry it.
Approved (specific use)
9 compoundsApproved by the FDA (or a major regulator) for at least one specific use. Approval covers that use only, not the other benefits listed.
Trial-backed
5 compoundsLarger randomized human trials exist, positive or negative, but no US approval for the uses discussed.
Early human
14 compoundsSmall, short, old, unblinded or single-group human studies.
Preclinical
10 compoundsMostly cell and animal studies. Human effects unknown.
Unstudied
10 compoundsNo direct studies of this product or blend. Anecdote and component data only.
What a label is not
A label describes the strength of the cited evidence for a compound as a whole. It is not advice, it is not a rating of safety, and it is not a rating of how well something works. A higher label does not mean a compound is safer or better for you. Listing a compound is not endorsement.
Read how evidence labels are assigned or look up a term in the glossary.